A 40 year old palatal neurofibroma

A case report

Abstract

Neurofi broma is a benign peripheral nerve sheath tumour, which arises from Schwann cells and perineural fi broblasts.
It is one of the most frequent tumours of neural origin and its presence is one of the clinical criteria for the diagnosis of
type 1 neurofi bromatosis (NF-I) also known as von Recklinghausen’s disease (VRD).
Oral localization is rarer showing an incidence ranging from 4 to 7% in most series of different authors. The most frequent
involvement site in oral neurofi bromatosis is the tongue, followed by the oral mucosa and fl oor of the mouth; palate
and maxillary-mandibular bones are a rare localization of the disease. The aim of this article is to report a case of
NF-I with a huge, quite old palatal involvement and its treatment.