The skin microbiome, dysbiosis and skin diseases

Abstract

The human skin harbors an extremely diverse microbiome, made up of countless microbes, including bacteria, fungi, viruses and mites. Collectively, these microorganisms play an important role in skin physiology, various immune responses and the formation of an antimicrobial safety net. Many factors influence the diversity of the skin microbiome. Alterations in the composition of commensal and symbiotic microorganisms can lead to imbalances in the microbiome and the resulting dysbiosis may play a role in the pathogenesis of various inflammatory skin diseases. In this review, we provide a brief summary of the relationship between microbial dysbiosis and inflammatory skin diseases.