Microbiome modulation inspired by phages – a therapeutic possibility in atopic dermatitis

* Szponzorált közlemény

Abstract

Phages are viruses that can infect bacteria host-specifically and support the balance of the normal, commensal microbiome. Lytic phages prevent the overgrowth of harmful bacteria by direct lysis. The activity of exogen endolysins
used in targeted therapies can led to the lysis of the bacterial cell within minutes, limiting the possible adaptation and the development of resistance. Phage terapies can be combined with symbiotic bacteria, with antibiotics and probiotics. In atopic dermatitis phage treatments can be a realistic therapeutic goal to reduce the colonisation of Staphylococcus aureus.