The use of non-thermal atmospheric plasma for the treatment of in situ cutaneous squamous cell carcinoma: a case series

Abstract

Despite its high incidence, cutaneous squamous cell carcinoma (SCC) remains a treatment challenge. Non-thermal, atmospheric pressure plasma (NTAP) is an emerging modality with a broad range of potential applications in dermatology, including the treatment of actinic keratosis. Given the close relationship between actinic keratosis and SCC, we treated three patients with biopsy-proven in-situ SCC, using NTAP. All three patients have tolerated the treatment very well, and they all reached full clinical resolution of their lesion after 2-5 treatment sessions. This case series highlights the potential role of NTAP in the treatment of SCC.